Every reason to discontinue lithium

Every reason to discontinue lithium

Lithium as a gold standard therapy for bipolar disorder is well known to have a number of medical comorbidities that impact renal, parathyroid, and thyroid function. Despite these medical comorbidities, there remains a group of lithium-responsive lithium-treated patients who have maintained mood stability for decades. The risk/benefit ratio of end organ toxicity/mood stability must be evaluated...

Learning to Reason: a Reason!-able Approach

How are general informal reasoning skills acquired? Little research has been done on this topic. Two hypotheses dominate. According to the strong situated learning hypothesis, there are no general informal reasoning skills (only contextor domainspecific skills) and so nothing can be done to improve them. According to the practice hypothesis, general informal reasoning can be improved through in...

Vision to reason

How to Reason Defeasibly

This paper describes the construction of a general-purpose defeasible reasoner that is complete for first-order logic and provably adequate for the argument-based conception of defeasible reasoning that I have developed elsewhere. Because the set of warranted conclusions for a defeasible reasoner will not generally be recursively enumerable, a defeasible reasoner based upon a rich logic like th...

To Continue or Discontinue the Project, That is the Question

Information systems and technology (IS/IT) projects are perceived as ventures that are prone to failure. An evaluation as part of IS/IT governance and control is highly important for stakeholders, to lessen the risk and the failure of such projects. However, decision-makers often encounter difficulties when evaluating and making decisions regarding the continuation of their projects. This study...